Dysport (Reloxin / Azzalure) vs. Botox
Dysport (also called Reloxin or Azzalure) is a new Botox-like treatment, which works the same way as Botox, relaxing muscles, which cause formation of facial wrinkles. The drug had been used in Europe for almost as long as Botox and approved for aesthetic use in 23 countries, before obtaining FDA approval in U.S. in April of 2009.
Though the main ingredient for both Botox and Dysport is botulinum toxin type A, they have some differences in effect and properties worth mentioning here. Technically Dysport is toxin diluted in lactose, whereas Botox is the same toxin diluted in sodium chloride.
The Dysport has a quicker onset of action than Botox (1-2 days against 3-5 days for Botox). Also the effect of Dysport is reported to last a little longer, than Botox’s. The Dysport procedure is likely to cost less, since the drug is provided is larger size vials, which makes it less expensive to the doctor.
Dysport showed to be more effective on younger patients, possibly due to age-related complications, such as delayed muscle response in older patients. Besides, Dysport has a little wider spread of action and affects a larger area, which leads to reduction in quantity of injections. Reduced number of injections might be favorable for the forehead, since it minimizes potential bruising. However, for the smaller areas, where more precision is required, Dysport may not be the best solution. Due to this property Dysport also requires a little different placement of injections, than Botox and makes it important for the doctor to stay away from certain structures.
Those who had success and no side effects from Botox injections may, however, experience them with Dysport, which side effects are yet to be fully discovered. The side effects protocol of both procedures is pretty much the same and includes risk of bruising, minor headache, incomplete effect, some dizziness and some risk of temporary drooping of eyelids or eyebrows (up to 1-2%). Dysport is likely to cause issues with eyelid dropping more often than Botox, which can be more injector dependent than product related.
Bottom line: Both Botox and Dysprot aren't permanent treatments and are pretty much identical. The results from Dysport might be faster, possibly last little longer and even slightly cheaper, but are not reported to be safer so far. Patients treated with Dysport seem to be more disappointed with the results, than those treated with Botox.